
Lisa Mosconi
A neuroscience-backed guide to eating and living for optimal brain health and cognitive longevity.
The human brain is about 80% water, more than any other organ.
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Section 1
10 Sections
Imagine a world where the greatest threat to our golden years is not just the ticking clock but a silent invader within our own brains.
It’s tempting to think that our fate is sealed by the genes we inherit, but the truth is far more hopeful.
Consider the concept of brain reserve, akin to an auxiliary fuel tank that allows the brain to function well despite accumulating insults. Just as a car with a bigger reserve can travel farther before refueling, a brain with a robust reserve can withstand more damage before symptoms appear. But this reserve is not infinite, and neglecting brain health accelerates its depletion.
In fact, the rapid rise in dementia cases worldwide is a sobering reminder of the consequences of ignoring brain health. More than 46 million people currently live with dementia, a number expected to nearly triple by 2050. This crisis touches families, communities, and healthcare systems alike, demanding urgent action.
But here lies the silver lining: scientific breakthroughs have illuminated how lifestyle changes, especially diet, can slow or even prevent cognitive decline.
So, as we begin this journey, let’s embrace the empowering truth that our brains are not doomed by genetics alone. Instead, they respond dynamically to our environment and habits. By understanding the looming crisis and recognizing our role in prevention, we lay the foundation for a lifetime of mental vitality.
Let us now delve deeper into the brain itself—its unique structure and remarkable demands—so that we may better understand how to nourish it well.
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Discover how everyday foods can protect your mind and extend cognitive longevity in ways science is just beginning to understand.
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Michael F. Roizen, M.D. and Michael Crupain, M.D., M.P.H.

Sara Gottfried, MD

Dr. Lisa Mosconi

Molly Carmel