
John J. Medina is a developmental molecular biologist and research consultant. He is an affiliate Professor of Bioengineering at the University of Washington School of Medicine and director of the Brain Center for Applied Learning Research at Seattle Pacific University. His work bridges brain science with practical applications in education and business.
Brain Rules reveals 12 neuroscience-backed principles to improve learning, productivity, and brain health through exercise, attention, memory, stress management, and sensory engagement.
Jack La Lanne, a fitness pioneer, swam towing 70 boats at age 70, demonstrating exercise benefits on brain and body.
Section 1
9 Sections
Imagine a world where the very act of moving your body lights up your mind. Our brains are not designed for stillness; they crave motion.
Exercise increases blood flow to the brain, delivering oxygen and glucose, the fuel that powers neurons. This increased circulation stimulates the growth of new blood vessels and encourages the production of Brain Derived Neurotrophic Factor (BDNF), a protein that acts like fertilizer for neurons, keeping them healthy and promoting new growth.
Scientific studies reveal that even moderate aerobic exercise—30 minutes, two to three times a week—can halve the risk of dementia and reduce Alzheimer's disease risk by over 60%. The benefits extend beyond the elderly; children who jog regularly show improved concentration and faster processing of visual stimuli. Exercise also regulates neurotransmitters like serotonin and dopamine, improving mood and helping combat depression and anxiety. In some cases, exercise alone has equaled antidepressant medication in effectiveness.
Yet, modern life often traps us in sedentary routines, sitting for hours in classrooms and offices. This mismatch between our evolutionary design and current lifestyle may explain widespread cognitive decline and mood disorders. The solution is simple but profound: move more. Integrating exercise into daily life—whether through recess in schools or treadmill desks at work—could restore our brains to their natural, vibrant state.
Stories of extraordinary comebacks, such as a golfer who overcame devastating injuries to win championships in his 50s, remind us of the brain's resilience when paired with physical activity.
As we move forward, let's carry this understanding with us, opening the door to the next chapter where we explore how our brains evolved to survive and thrive in a world of constant change.
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